Peptides having atrial natriuretic factor activity

Details Peptides having atrial natriuretic factor activity Peptides having atrial natriuretic factor activity

C - Chemistry, Metallurgy

07

K

C07K 14/58 (2006.01) A61K 38/22 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2045420

9451P/5879A 18005 TITLE OF THE INVENTION PEPTIDES HAVING ATRIAL NATRIURETIC FACTOR ACTIVITY ABSTRACT OF THE DISCLOSURE Atrial natriuretic factor analogs containing N-alkylated amino acids and showing enhanced potency and increased metabolic stability. These analogs have natriuretic, diuretic and vasorelaxant activity, making them suitable for treating congestive heart failure and renal hypertension.

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