Treatment of severe pneumonia by administration of tissue...

Details Treatment of severe pneumonia by administration of tissue... Treatment of severe pneumonia by administration of tissue...

A - Human Necessities

61

K

A61K 38/16 (2006.01) A61K 38/57 (2006.01)

Patent

CA 2463655

Methods for prophylactically or therapeutically treating severe pneumonia involve administration of tissue factor pathway inhibitor (TFPI) or a TFPI analog to patients suffering from or at risk of developing this condition. The methods involve the use of continuous intravenous infusion of TFPI or a TFPI analog, preferably at low doses to avoid adverse side effects.

La présente invention concerne des méthodes de traitement par voie prophylactique et thérapeutique de la pneumonie grave. Lesdites méthodes consistent à administrer un inhibiteur du mécanisme d'action du facteur tissulaire (TFPI) ou un analogue de TFPI à des patients souffrant de ou risquant de développer ladite pathologie. Lesdites méthodes consistent à utiliser l'infusion intraveineuse en continu d'un TFPI ou d'un analogue de TFPI, de préférence à faibles doses pour éviter des effets indésirables.

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