Topical antiviral formulations

Details Topical antiviral formulations Topical antiviral formulations

A - Human Necessities

61

K

A61K 9/06 (2006.01) A61K 9/12 (2006.01) A61K 9/16 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2570877

The present invention relates to formulations of nucleotide reverse transcriptase inhibitors (NRTIs), preferably [2-(6-Amino-purin-9-yl)-1-methyl- ethoxymethyl]-phosphonic acid (tenofovir, PMPA), or a physiologically functional derivative thereof, suitable for topical application and their use in the prevention of HIV infections.

La présente invention concerne des formulations d'inhibiteurs de nucléotide transcriptase inverse (NRTI), de préférence l'acide [2-(6-amino-purin-9-yl)-1-méthyl-éthoxyméthyl]-phosphonique (ténofovir, PMPA), ou un dérivé physiologiquement fonctionnel de ceux-ci, adaptées pour une application topique et leur utilisation dans la prévention des infections à VIH.

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