Tricyclic dihydrobenzofuran derivatives, process for...

Details Tricyclic dihydrobenzofuran derivatives, process for... Tricyclic dihydrobenzofuran derivatives, process for...

C - Chemistry, Metallurgy

07

D

C07D 491/048 (2006.01) A61K 31/407 (2006.01) A61K 31/454 (2006.01) A61K 31/55 (2006.01) A61P 9/08 (2006.01) A61P 9/10 (2006.01) A61P 13/02 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2382413

Compounds represented by general formula (1) or salts thereof exhibit excellent inhibitory activity against the formation of peroxylipid and are useful as inhibitors against the formation thereof. In said formula, A is a nonaromatic five- to seven-membered nitrogenous heterocycle which may be additionally substituted; B is a benzene ring which is additionally substituted; C is a dihydrofuran ring which may be additionally substituted; and R is hydrogen or acyl.

L'invention concerne des composés représentés par la formule générale (1) ou des sels de ceux-ci, qui possèdent une excellent activité inhibitrice contre la formation de peroxylipide et qui sont utiles en tant qu'inhibiteurs de la formation de peroxylipide. Dans ladite formule, A représente un hétérocycle azoté à cinq à sept éléments, pouvant être éventuellement substitué; B représente un cycle benzénique substitué; C représente un cycle dihydrofuran éventuellement substitué et R représente hydrogène ou acyle.

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