Use of milnacipran or a pharmaceutically acceptable salt...

Details Use of milnacipran or a pharmaceutically acceptable salt... Use of milnacipran or a pharmaceutically acceptable salt...

A - Human Necessities

61

K

A61K 31/381 (2006.01) A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/165 (2006.01) A61K 31/195 (2006.01) A61K 31/198 (2006.01) A61K 31/38 (2006.01) A61K 31/485 (2006.01) A61K 31/496 (2006.01) A61K 31/55 (2006.01) A61K 31/551 (2006.01) A61K 31/5513 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2483093

Methods for the prevention or treatment of stress-related disor ders by administering a therapeutically effective amount of a dual serotonin/norepinephrine reuptake inhibitor to an individual under stress are described. A triple monoamine reuptake inhibitor for serotonin/noradrenaline/dopamine may also be administered to an individual at risk for a stress-related disorder. In a preferred embodiment the compound is milnacipran and is prophylactically administered at an effective amount to delay or prevent stress- related disorders in an individual at risk.

La présente invention concerne des procédés destinés à la prévention ou au traitement de troubles liés au stress. En l'occurrence, à un individu soumis à un stress, on administre une quantité thérapeutiquement suffisante d'un inhibiteur double de recaptage de la sérotonine et de la norépinéphrine. On peut également administrer, à un individu présentant un risque de trouble lié au stress, un inhibiteur monoaminique triple de recaptage de la sérotonine, de la noradrénaline et de la dopamine. Selon un mode de réalisation préféré, le composé est le milnacipran que l'on administre de façon préventive en quantité suffisante pour retarder ou prévenir les troubles liés au stress chez un individu présentant un tel risque.

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