In-situ preparation of diisopinocamphenyl chloroborane

Details In-situ preparation of diisopinocamphenyl chloroborane In-situ preparation of diisopinocamphenyl chloroborane

C - Chemistry, Metallurgy

07

C

C07C 67/31 (2006.01) C07C 29/143 (2006.01) C07C 69/736 (2006.01) C07C 253/30 (2006.01) C07C 255/37 (2006.01) C07D 307/33 (2006.01) C07F 5/02 (2006.01) C07F 9/12 (2006.01)

Patent

CA 2050820

87/CCP34 18193 TITLE OF THE DISCLOSURE IN-SITU PREPARATION OF DIISOPINOCAMPHEYL CHLOROBORANE ABSTRACT OF THE DISCLOSURE The present invention is directed to in-situ preparation of diisopinocamphenylchloroborane, and the use of same in the reduction of prochiral ketones to optically active alcohols such as those of formula B. Image B The compound of Formula B is useful in the production 2,5-diaryltetrahydrofurans useful as PAF antagonists.

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