Solid phase test for endotoxin

Details Solid phase test for endotoxin Solid phase test for endotoxin

G - Physics

01

N

G01N 33/579 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2327169

A solid phase apparatus, for detection of endotoxin in a liquid sample using reagents located within solid support material, comprises endotoxin sensitive reagent and buffer components. When a liquid sample containing endotoxin is applied to the apparatus the endotoxin sensitive reagent reacts with the endotoxin to form at least one product, and following contact of the at least one product with buffer components, an endotoxin indicator is formed. Also disclosed are a method and a kit to test for endotoxin.

L'invention concerne un appareil à phase solide permettant de détecter l'endotoxine dans un échantillon liquide, à l'aide de réactifs situés à l'intérieur d'un support solide, cet appareil comprenant un réactif sensible à l'endotoxine ainsi que des composants tampons. Lorsque l'on applique à cet appareil un échantillon liquide contenant ladite endotoxine, le réactif sensible à l'endotoxine réagit avec cette dernière de manière à former au moins un produit, le contact de ce produit et desdits composants tampons permettant par ailleurs de former un indicateur d'endotoxine. L'invention concerne également une méthode et un kit d'essai permettant de détecter l'endotoxine.

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