C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 235/02 (2006.01) A61K 31/4184 (2006.01) A61K 31/4439 (2006.01) A61K 31/4709 (2006.01) A61K 31/498 (2006.01) A61P 25/06 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2518843
The present invention is directed to compounds that are antagonists of CGRP receptors and that are useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
L'invention concerne des composés qui sont des antagonistes des récepteurs de CGRP et qui servent dans le traitement ou la prévention de maladies impliquant le CGRP, par exemple la céphalée, la migraine et la céphalée vasculaire de Horton. L'invention concerne également des compositions pharmaceutiques renfermant ces composés et l'utilisation de ces composés et compositions dans la prévention ou le traitement de ces maladies impliquant le CGRP.
Bell Ian M.
Theberge Cory R.
Zartman C. Blair
Zhang Xu-Fang
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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