Process for the preparation of clavulanic acid

Details Process for the preparation of clavulanic acid Process for the preparation of clavulanic acid

C - Chemistry, Metallurgy

12

P

C12P 17/18 (2006.01)

Patent

CA 2251596

A process for preparation of clavulanic acid comprising fermentation of a clavulanic acid producing species of Streptomyces in a fermentation broth containing assimilable sources of carbon and nitrogen, wherein the concentration of phosphorus in the fermentation broth is less than 0.15 % w/v.

L'invention a pour objet un procédé de préparation d'acide clavulanique, qui comprend la fermentation d'une espèce de Streptomyces produisant de l'acide clavulanique dans un bouillon de fermentation contenant des sources assimilables de carbone et d'azote, la concentration de phosphore dans ledit bouillon de fermentation étant inférieure à 0,15 % en poids par volume.

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