Chemotactic factor inhibitor for modulating inflammatory...

Details Chemotactic factor inhibitor for modulating inflammatory... Chemotactic factor inhibitor for modulating inflammatory...

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 31/7105 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) A61P 29/00 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2489860

The present invention relates to compounds and methods for modulating, reducing or inhibiting, inflammatory reactions in a patient. Particularly, inflammatory reactions that are targeted by the present invention are cell migration, secretion of toxic products and proteolysis at a site of inflammation. Reduction of inflammation manifestations and reactions occurs by using an anti-S100 polynucleotide or polypeptide inhibitor or antagonist, which is essentially targeted against S100A8, S100A9 or S100A12, alone or in combination with other inhibitors of chemokines or immune modulating products.

L'invention concerne des composés et des procédés destinés à moduler, réduire ou inhiber des réactions inflammatoires chez un patient. L'invention cible particulièrement les réactions inflammatoires concernant la migration cellulaire, la sécrétion de produits toxiques et la protéolyse à un site d'inflammation. La réduction des réactions et des manifestations inflammatoires se produit grâce à un polynucléotide anti-S100 ou à un inhibiteur ou à un antagoniste de polypeptide, essentiellement dirigé contre S100A8, S100A9 ou S100A12, seul ou en combinaison avec d'autres inhibiteurs de chimiokines ou avec des produits immunomodulants.

Affiliated with

Also associated with

Rating

Chemotactic factor inhibitor for modulating inflammatory... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chemotactic factor inhibitor for modulating inflammatory..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemotactic factor inhibitor for modulating inflammatory... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1953144