Compositions and methods for inhibiting cell death

Details Compositions and methods for inhibiting cell death Compositions and methods for inhibiting cell death

C - Chemistry, Metallurgy

07

D

C07D 235/20 (2006.01) A61K 31/4184 (2006.01) A61K 31/506 (2006.01) A61P 43/00 (2006.01) C07D 233/54 (2006.01) C07D 235/08 (2006.01) C07D 235/10 (2006.01) C07D 235/16 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2375843

Compounds, pharmaceutical compositions, and methods of use are described which are effective in inhibiting cell death, particularly apoptotic cell death. The compositions may be used for prevention and treatment of injuries associated with cell death, including ischemia, such as results from stroke or myocardial infarction, trauma, neurodegeneration, and inflammation.

La présente invention concerne des composés, des compositions pharmaceutiques, et des méthodes d'utilisation qui sont efficaces pour inhiber la mort cellulaire, en particulier la mort cellulaire par apoptose. Ces compositions conviennent pour la prévention et le traitement de blessures associées à la mort de cellules, notamment l'ischémie, telle que celle qui résulte d'un accident vasculaire ou d'un infarctus du myocarde, d'un traumatisme, d'une maladie neurodégénérative et d'une inflammation.

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