Treatment of diseases involving erbb2 kinase overexpression

A - Human Necessities – 61 – K

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A61K 31/35 (2006.01)

Patent

CA 2541548

The invention relates to compositions containing polyphenols such as flavanols and their related oligomers, and methods for treating conditions associated with ErbB2 kinase overexpression, for example, treatment of cancers involving ErbB2 kinase overexpression. Fig. 2 represents results from the real time PCR experiments verifying reduced expression of ErbB2 kinase in HAEC in the presence of procyanidins.

Cette invention concerne des compositions contenant des polyphénols, tels que les flavanols et leurs oligomères apparentés; et des méthodes de traitement d'états associés à la surexpression de la kinase ErbB2, notamment le traitement de cancers impliquant la surexpression de la kinase ErbB2.

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