Process for selective removal of salivary .alpha.-amylase...

Details Process for selective removal of salivary .alpha.-amylase... Process for selective removal of salivary .alpha.-amylase...

C - Chemistry, Metallurgy

12

N

C12N 9/26 (2006.01) A61K 39/44 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2055627

ABSTRACT "Process for selective removal of salivary .alpha.-amylase and assay for pancreatic .alpha.-amylase" Inter alia, a process for the selective removal of salivary .alpha.-amylase from a sample comprising salivary .alpha.-amylase and pancreatic .alpha.-amylase characterised in that there is used a monoclonal antibody against salivary .alpha.-amylase, which is immobilised or is coupled to a physically seperable or seperate support and which exhibits a binding affinity towards salivary .alpha.-amylase of at elast 1 x 107 1/m and a cross-reactivity with pancreatic .alpha.-amylase of less than 1% is disclosed. The remaining pancreatic .alpha.-amylase may be assayed.

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