A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/13 (2006.01) A61K 31/00 (2006.01)
Patent
CA 2436311
The present invention relates to compositions and methods for treating a human patient afflicted with a neuropsychiatric disorder. Specifically, the invention provides for compositions and methods of modulating or antagonizing the activity of neuronal NMDA receptors, wherein such antagonistic activity is capable of modulating the glutamate induced excitatory response of the neurons, thereby inhibiting an excitotoxic effect, promoting a neurotrophic effect, and thereby providing a therapeutic effect that treats the neuropsychiatric disorder.
La présente invention concerne des compositions et des méthodes de traitement d'un patient humain atteint d'un trouble neuropsychiatrique. L'invention concerne plus particulièrement des compositions et des méthodes qui modulent ou antagonisent l'activité des récepteurs neuronaux de NMDA. Cette activité antagoniste peut moduler la réaction excitatrice des neurones induite par le glutamate, ce qui inhibe un effet excitotoxique, produit un effet neurotrophique, et induit un effet thérapeutique pouvant traiter le trouble neuropsychiatrique.
Adamas Pharmaceuticals Inc.
Neuromolecular Inc.
Smart & Biggar
LandOfFree
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