Microfluidic system for analyzing nucleic acids

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) B01L 3/00 (2006.01) C07H 21/00 (2006.01) C12M 1/34 (2006.01) C12M 1/38 (2006.01)

Patent

CA 2444200

A system, including methods and apparatus, for microfluidic analysis of a nucleic acid target in a nucleic acid mixture. The system includes a method to preselect the target from the mixture before amplification. Preselection enriches the mixture for the target by retaining the target on a target-selective receptor and then removing unretained non-target nucleic acids. The preselected target then may be amplified from the enriched mixture and assayed. Devices configured to carry out the method are also disclosed.

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