Substituted benzamide derivatives and their use as...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 217/22 (2006.01) A61K 31/40 (2006.01) A61K 31/47 (2006.01) A61K 31/472 (2006.01) A61K 31/55 (2006.01) C07D 209/44 (2006.01) C07D 217/04 (2006.01) C07D 223/16 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2258238

The invention relates to substituted benzamido-heterocyclic compounds of general formula (I) having an alkoxy substituent at the C2 position of the benzamido group and various substituents at positions C4 and C5, being optionally substituted on the N atom of the heterocyclic system, and where the unsaturated ring of the heterocyclic system is a 5, 6, 7 or 8-membered ring. Also to the use of these compounds as anticonvulsants in certain medical conditions, and to processes for making them.

L'invention concerne des composés benzamido-hétérocycliques substitués, de formule générale (I), comportant un substituant alcoxy en position C2 du groupe benzamido et divers substituants aux positions C4 et C5; éventuellement substitués sur l'atome N du système hétérocyclique; et dans lesquels le noyau insaturé du système hétérocyclique est un noyau à 5, 6, 7 ou 8 éléments. L'invention concerne également l'utilisation de ces composés comme anticonvulsivants dans certains troubles médicaux, ainsi que les procédés permettant de les fabriquer.

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