Polycationic carbohydrates as immunostimulants in vaccines

A - Human Necessities – 61 – K

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Details

A61K 39/39 (2006.01) A61K 9/00 (2006.01) A61K 9/127 (2006.01) A61K 9/50 (2006.01) A61K 39/02 (2006.01) A61K 39/05 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2366216

A polycationic carbohydrate such as chitosan, or a pharmaceutically acceptable derivative thereof, are used as immunostimulants. Vaccine compositions containing these polycationic carbohydrates, in particular in particles such as microparticles or liposomes are also described and claimed. Methods of treatment and the use of the polycationic carbohydrates as immunostimulants in the production of vaccines are further aspects described and claimed.

Un glucide polycationique tel que le chitosane, ou un dérivé acceptable sur le plan pharmaceutique de celui-ci, est utilisé comme immunostimulant. Des compositions de vaccin contenant ces glucides polycationiques, notamment sous la forme de particules telles que des microparticules ou des liposomes sont également décrites et revendiquées. Des méthodes de traitement ainsi que l'utilisation des glucides polycationiques en tant qu'immunostimulants dans la production de vaccins constituent d'autres aspects décrits et revendiqués.

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