Human mast cell-expressed membrane protein

Details Human mast cell-expressed membrane protein Human mast cell-expressed membrane protein

A - Human Necessities

61

K

A61K 38/00 (2006.01) A61K 39/395 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2531073

The present invention relates to GPR91, a purinergic receptor-like polypeptide, its expression in mast cells, and its use in the diagnosis and/or treatment of mast cell mediated diseases, including allergic and nonallergic asthma, chronic obstructive pulmonary disease (COPD), allergic rhinitis, anaphylaxis, allergic gastrointestinal disease, atopic dermatitis, rheumatoid arthritis, and other allergic, autoimmune and inflammatory diseases. The invention also includes methods of screening of agonists and/or antagonists of the GPR91 receptor.

La présente invention se rapporte à GPR91, un polypeptide de type récepteur purinergique, à son expression dans des mastocytes, et à son utilisation pour le diagnostic et/ou le traitement de maladies médiées par des mastocytes, et notamment l'asthme allergique et non allergique, les broncho-pneumopathies chroniques obstructives (COPD), les rhinites allergiques, l'anaphylaxie, les maladies gastro-intestinales allergiques, les dermatites atopiques, la polyarthrite rhumatoïde et d'autres maladies allergiques, auto-immunes et inflammatoires. L'invention se rapporte également à des procédés de criblage d'agonistes et/ou d'antagonistes du récepteur GPR91.

Affiliated with

Also associated with

Rating

Human mast cell-expressed membrane protein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Human mast cell-expressed membrane protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human mast cell-expressed membrane protein will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1957811