Caveolin peptides and their use as therapeutics

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/47 (2006.01) A61K 38/17 (2006.01) A61P 9/00 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C12N 9/02 (2006.01) C12N 15/62 (2006.01) G01N 33/573 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2421041

The present invention relates generally to compositions and methods useful for treating various conditions and afflictions, such as inflammation and cancer. More specifically, the present invention relates to compositions and methods of treatment which utilize peptides comprising at least one caveolin scaffolding domain. Even more specifically, the present invention relates to compositions of fusion peptides comprising the antennapedia homeodomain fused to a caveolin scaffolding domain and to methods of using these peptides to treat various conditions and afflictions.

L'invention concerne, de façon générale, des compositions et des méthodes utilisées pour le traitement de divers états et afflictions, tels que inflammations et cancers. Plus spécifiquement, l'invention concerne des compositions et des méthodes de traitement utilisant des peptides comprenant au moins un domaine support de cavéoline. Plus particulièrement, l'invention concerne des compositions de peptides de fusion comprenant l'homéodomaine antennapedia fusionné à un domaine support de cavéoline, ainsi que des méthodes d'utilisation de ces peptides en vue de traiter divers états et afflictions.

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