Pyrazine compounds as crf modulators

Details Pyrazine compounds as crf modulators Pyrazine compounds as crf modulators

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01) A61K 31/497 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) C07D 241/12 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2499133

Disclosed are pyrazine derivatives, pharmaceutical compositions containing them, and methods of using them to treat a disorder or condition the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as an anxiety-related disorder or affective disorder.

Cette invention concerne des dérivés de pyrazine, des compositions pharmaceutiques renfermant ces dérivés et des méthodes d'utilisation desdits dérivés pour le traitement d'une manifestation pathologique ou d'une maladie, relevant de l'angoisse ou d'un trouble émotionnel par exemple, au moyen d'un antagoniste du récepteur du facteur de libération de la corticotropine (CRF).

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