Aromatic amides

Details Aromatic amides Aromatic amides

C - Chemistry, Metallurgy

07

C

C07C 233/36 (2006.01) A61K 31/167 (2006.01) A61K 31/445 (2006.01) A61K 31/47 (2006.01) A61P 25/28 (2006.01) C07C 247/16 (2006.01) C07D 215/46 (2006.01) C07D 295/13 (2006.01)

Patent

CA 2373173

Aromatic and heteroaromatic amides of formula (I) where R1, R2 and R3 can be alkyl, X is alkylene, and R4 is an unsubstituted or substituted aromatic or heteroaromatic group such as naphthyl or fluorenyl, are CNS agents useful for treating pain, depression, anxiety, seizures, and schizophrenia.

L'invention concerne des amides aromatiques et hétéroaromatiques de formule (I) dans laquelle R¿1?, R¿2? et R¿3? peuvent représenter alkyle, X représente alkylène et R?4¿ représente un groupe aromatique ou hétéroaromatique non substitué ou substitué, tel que naphtyle ou fluroényle. Les amides de la présente invention sont des agents actifs sur le système nerveux central, utiles pour traiter la douleur, la dépression, l'anxiété, les crises d'épilepsie, et la schizophrénie.

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