Methods of inhibiting environmental estrogens

Details Methods of inhibiting environmental estrogens Methods of inhibiting environmental estrogens

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/4535 (2006.01)

Patent

CA 2210940

A method of inhibiting effects of environmental estrogens comprising administering to a human or other animal in need thereof an effective amount of a compound having formula (I), wherein R1 and R3 are independently hydrogen, -CH3, (a) or (b), wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.

Procédé d'inhibition des effets provoqués par des oestrogènes provenant de l'environnement, qui consiste à administrer à l'homme ou un autre animal, une quantité efficace d'un composé représenté par la formule (I) dans laquelle R<1> et R<3> représentent indépendamment hydrogène, -CH3, (a) ou (b), où Ar représente éventuellement phényle substitué; R<2> est choisi dans le groupe constitué par pyrrolidine, hexaméthylèneimino et pipéridino; ou son sel de solvate acceptable pharmaceutiquement.

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