Retroviral vectors with foreign-sequence insertion between...

Details Retroviral vectors with foreign-sequence insertion between... Retroviral vectors with foreign-sequence insertion between...

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) A61K 48/00 (2006.01) C07K 14/15 (2006.01) C12N 5/10 (2006.01) C12N 15/10 (2006.01) C12N 15/867 (2006.01) C12P 21/00 (2006.01)

Patent

CA 2357081

The subject of the invention is retroviral gene transfer vectors in which foreign sequences are introduced between the retroviral primer binding site (PBS) and the retroviral splice donor (SD). The efficiency of gene expression is improved by this modification, and the vectors are characterized by an increased reliability during use.

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