A method of weak partitioning chromatography

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 1/22 (2006.01) B01D 15/00 (2006.01) B01D 53/02 (2006.01) C07K 1/14 (2006.01) C07K 16/00 (2006.01)

Patent

CA 2601062

This invention relates to methods of using weak partitioning chromatography for the purification of a product from a load fluid containing one or more impurities. Further, the invention relates to methods of weak partitioning chromatography defined by operating conditions which cause a medium to bind least 1 mg of product per mL of medium, or alternatively, defined by a partition coefficient of at least 0.1.

L'invention concerne des procédés d'application de chromatographie à faible séparation pour purifier un produit dans un liquide de charge contenant une ou plusieurs impuretés. De plus, l'invention concerne des procédés de chromatographie à faible séparation caractérisés par des conditions d'exploitation qui entraînent la liaison d'un milieu avec au moins 1 mg de produit par ml de milieu, ou dans une variante, par un coefficient de séparation d'au moins 0,1.

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