Method for maldi-tof-ms analysis and/or sequencing of...

Details Method for maldi-tof-ms analysis and/or sequencing of... Method for maldi-tof-ms analysis and/or sequencing of...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2430648

The present invention is related to a method for MALDI-TOF-MS analysis and/or sequencing of oligoribonucleotides. The present invention is also related to a method for determining the DNA nucleotide sequence using MALDI-TOF-MS, and a method for determining polymorphism using MALDI-TOF-MS. The present invention provides a kit for analysing and/or sequencing a DNA template or a RNA transcription product and/or for determining polymorphism by MALDI-TOF-MS.

L'invention concerne un procédé d'analyse et/ou séquençage d'oligoribonucléotides, par spectrométrie de masse par temps de vol avec désorption-ionisation par impact laser assistée par matrice (MALDI-TOF-MS), ainsi qu'un procédé de détermination d'une séquence nucléotidique d'ADN mettant en oeuvre MALDI-TOF-MS. L'invention concerne encore un procédé de détermination de polymorphisme au moyen de MALDI-TOF-MS, ainsi qu'une trousse d'analyse et/ou de séquençage d'une matrice ADN ou d'un produit de transcription d'ARN, et/ou de détermination de polymorphisme, par l'intermédiaire de MALDI-TOF-MS.

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