Method of producing rough strains of bacteria and uses thereof

C - Chemistry – Metallurgy – 12 – N

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C12N 1/20 (2006.01) A61K 39/04 (2006.01) A61K 39/39 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2633127

The present invention relates to a method of producing rough strains of a bacterium, such as Mycobacterium obuense, said method comprising exposing said bacterium to a sulfone and/or sulfonamide (such as 4,4'-Diaminodiphenyl sulfone or an ana-logue thereof). A rough strain of Mycobacterium obuense producible by said method and uses thereof. In particular, uses of a rough strain of Mycobacterium obuense deposited under the Budapest Treaty at the NCTC with the accession number NCTC 13365.

L'invention concerne un procédé de production de souches rugueuses d'une bactérie, telle que Mycobacterium obuense, le procédé consistant à exposer la bactérie à un sulfone et/ou sulfonamide (tel que le 4,4'-Diaminodiphényl sulfone ou un analogue de celui-ci). L'invention concerne également une souche rugueuse deMycobacterium obuense pouvant être produite au moyen dudit procédé et des utilisations de celle-ci. Plus précisément, des utilisations d'une souche rugueuse de<I/> Mycobacter

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