Method of inactivating prions

Details Method of inactivating prions Method of inactivating prions

A - Human Necessities

61

L

A61L 2/04 (2006.01) A23L 3/00 (2006.01) A23L 3/015 (2006.01) A61L 2/00 (2006.01) C07K 1/113 (2006.01)

Patent

CA 2492034

A method for inactivating prions comprises subjecting a substrate containing prions to one or more pulses of ultra high pressures for a predetermined period of time. The pressures are preferably at least 480 MPa for at least one second. The substrate and the prions are adiabatically heated to elevated temperatures at which the prions are inactivated.

L'invention concerne un proc~d~ d'inactivation de prions, qui consiste ~ exposer un substrat contenant des prions ~ une ou plusieurs impulsions de pressions ~ tr­s haute puissance pendant une dur~e d~termin~e. Ces pressions ont, de pr~f~rence, une puissance d'au moins 480 Mpa et sont appliqu~es pendant au moins une seconde. Le substrat et les prions sont adiabatiquement chauff~s ~ des temp~ratures ~lev~es auxquelles les prions sont inactiv~s.

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