G-protein coupled receptors

Details G-protein coupled receptors G-protein coupled receptors

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2402940

The invention provides isolated nucleic acid and amino acid sequences of four novel G-protein coupled receptors that are amplified in breast cancer cells, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of G-protein coupled receptors.

Cette invention concerne des séquences d'acides nucléiques et d'acides aminés isolés pour quatre nouveaux récepteurs liés à la la protéine G qui se rencontrent sous une forme amplifiée dans les cellules du cancer du sein, des anticorps de tels récepteurs, des méthodes de détection desdits acides nucléiques et récepteurs ainsi que des méthodes de recherche systématique de modulateurs des récepteurs liés à la protéine G.

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