Loading technique for preparing drug containing liposomes

Details Loading technique for preparing drug containing liposomes Loading technique for preparing drug containing liposomes

A - Human Necessities

61

K

A61K 9/127 (2006.01) B01J 13/02 (2006.01)

Patent

CA 2111593

2111593 9300888 PCTABS00019 A process for loading of cationic, anionic or ionizable drugs through lipid bilayer membranes in the absence of a pH gradient comprises the formation of liposomes in an aqueous medium containing a combination of either the salt of an anion with high membrane permeability and a cation with low membrane permeability if the compound to be entrapped is an anionic drug or has an anionic potential; or the salt of a cation with high membrane permeability and an anion with low membrane permeability if the compound to be entrapped is a cationic drug or has a cationic potential.

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