Anti-tumor compounds with angeloyl groups

C - Chemistry – Metallurgy – 07 – J

Patent

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C07J 53/00 (2006.01) A61K 31/704 (2006.01) C07H 15/24 (2006.01)

Patent

CA 2579231

Novel compounds such as compounds designated herein as Xanifolia-Y or -Y3, - Y1, -Y2, -Y8, -Y9 and -Y10 are disclosed. These compounds have anticancer activity. The compounds of the present invention are obtainable from plants in the sapindaceae family, such as Xanthoceras sorbifolia, or other natural sources or products. The compounds of the present invention may also be synthesized chemically, Formula (I).

L'invention concerne de nouveaux composés, tels que les composés désignés ici sous le nom de Xanifolia-Y ou Y3, -Y1, -Y2, -Y8, -Y9 et Y10. Ces composés possèdent une activité anticancéreuse. Les composés de la présente invention peuvent être obtenus à partir de végétaux de la famille des sapindacées, tels que Xanthoceras sorbifolia, ou d'autres sources ou produits naturels. Les composés de la présente invention peuvent également être synthétisés par voie chimique.

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