Compounds active at the glucocorticoid receptor

Details Compounds active at the glucocorticoid receptor Compounds active at the glucocorticoid receptor

C - Chemistry, Metallurgy

07

C

C07C 59/68 (2006.01) A61K 31/10 (2006.01) A61K 31/136 (2006.01) A61K 31/18 (2006.01) A61K 31/192 (2006.01) A61K 31/235 (2006.01) A61K 31/404 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07C 59/72 (2006.01) C07C 69/736 (2006.01) C07C 69/88 (2006.01) C07C 215/50 (2006.01) C07C 217/56 (2006.01) C07C 217/58 (2006.01) C07C 217/86 (2006.01) C07C 229/60 (2006.01) C07C 233/25 (2006.01) C07C 233/75 (2006.01) C07C 235/48 (2006.01) C07C 311/17 (2006.01) C07C 317/18 (2006.01) C07C 323/16 (2006.01) C07C 323/18

Patent

CA 2393583

This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in therapy and in the regulation of metabolism, especially lowering blood glucose levels. The compounds referred to are compounds according to the formula (I).

L'invention porte sur de nouveaux composés qui sont des antagonistes sélectifs du récepteur glucocorticoïde du foie, sur les procédés de préparation de ces composés et sur leurs procédés d'utilisation en thérapie et dans la régulation du métabolisme, notamment la réduction des taux de glucose dans le sang. Ces composés sont des composés de la formule (I).

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