A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/39 (2006.01) A61K 31/335 (2006.01) A61K 45/06 (2006.01) A61K 9/107 (2006.01) A61K 9/127 (2006.01)
Patent
CA 2425310
The present invention relates to novel adjuvant compositions for use in vaccines. In particular, the adjuvant compositions of the present invention comprise a combination of an immunostimulatory oligonucleotide and a tocol. Also provided by the present invention are vaccines comprising the adjuvant compositions of the present invention and at least one antigen. Further provided are methods of manufacture of the adjuvant compositions and vaccines of the present invention and their us as medicaments. Additionally, the present invention provides methods of treating an individual susceptible to or suffering from a disease by the parenteral or mucosal administration of the vaccines of the present invention.
L'invention concerne des compositions adjuvantes s'utilisant dans des vaccins. Les compositions adjuvantes de l'invention sont une combinaison d'un oligonucléotide immunostimulateur et d'un tocol. L'invention concerne également des vaccins contenant ces compositions adjuvantes et au moins un antigène. Par ailleurs, cette invention porte sur des procédés de fabrication de compositions adjuvantes et de vaccins, et sur leur utilisation en tant médicaments. L'invention concerne enfin des procédés de traitement d'un individu susceptible de souffrir ou souffrant d'une maladie par administration parentérale ou mucosale des vaccins de l'invention.
Garcon Nathalie
Gerard Catherine Marie Ghislaine
Stephenne Jean
Glaxosmithkline Biologicals S.a.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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