Spiro '1-azabicyclo '2.2.2!octan-3,5'-oxazolidin-2'one!...

C - Chemistry – Metallurgy – 07 – D

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C07D 498/20 (2006.01) A61K 31/439 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2531510

Compounds of formula (I) and pharmaceutically-acceptable salts thereof, wherein Arl, A and Ar2 are as defined in the specification, pharmaceutical compositions and formulations containing them, methods of using them to treat diseases and conditions either alone or in combination with other therapeutically-active compounds or substances, processes and intermediates used to prepare them, uses of them as medicaments for therapy, uses of them in the manufacture of medicaments and uses of them for diagnostic and analytic purposes.

L'invention concerne des composés représentés par la formule (I) ainsi que des sels pharmaceutiquement acceptables de ceux-ci. Ar?l¿, A et Ar?2¿ sont tels que définis dans la spécification. L'invention concerne également des compositions pharmaceutiques et des préparations contenant ces composés et ces sels, des procédés d'utilisation de ceux-ci pour traiter des maladies et des états pathologiques seuls ou combinés à d'autres composés ou substances actifs au niveau thérapeutique, des procédés et des substances intermédiaires utilisés pour la préparation de ces composés et de ces sels, leur utilisation dans la fabrication de médicaments ainsi que dans des buts diagnostiques et analytiques.

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