Device for introducing pores into biological materials

C - Chemistry – Metallurgy – 12 – M

Patent

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Details

C12M 1/42 (2006.01) A61N 2/02 (2006.01) C12N 13/00 (2006.01)

Patent

CA 2382434

The present invention relates to a device for creating pores in a biomaterial, such as a cell or tissue in a sample. The device uses an alternating magnetic field that increases the thermal or kinetic energy of magnetic particles present in the sample. The magnetic particles then create pores in the membrane surrounding the biostructure. Subsequently, the pores may be employed for the introduction of particles into the biostructure. In preferred embodiments the device is equipped with temperature control.

La présente invention concerne un dispositif destiné à créer des pores dans un matériau biologique, tel qu'une cellule ou un tissu dans un échantillon. Ce dispositif utilise un champ magnétique alternatif qui augmente l'énergie thermique ou cinétique des particules magnétiques présentes dans l'échantillon. Ces particules magnétiques créent ensuite des pores dans la membrane qui entoure la biostructure. Ces pores peuvent ensuite être utilisés pour introduire des particules dans cette biostructure. Dans un mode de réalisation préféré de l'invention, ce dispositif est pourvu d'un capteur permettant de surveiller la température.

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