Process and system for controlled-release drug delivery

Details Process and system for controlled-release drug delivery Process and system for controlled-release drug delivery

A - Human Necessities

61

K

A61K 9/22 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 47/10 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2363902

A controlled-release dosage form for a phamaceutically-active agent comprises a core, in which the agent is dispersed, surrounded by a diffusion-limiting sleeve. The agent is released at a zero-order or approximately linear rate because the release rate of the agent will be governed entirely by erosion from exposed core surfaces; the surface area of which does not change substantially during the release process. Such a product may be made by co-extruding the core and sleeve material and slicing the extrudate.

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