Methods for predicting and monitoring response to cancer...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2568732

The invention provides novel compositions, methods and uses, for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasia and breast cancer. The invention further relates to genes that are differentially expressed in breast tissue of breast cancer patients versus those of normal "healthy" tissue. Differentially expressed genes for the identification of patients which are likely to respond to chemotherapy are also provided.

L'invention concerne des nouvelles compositions, des méthodes et utilisations, pour la prédiction, le diagnostic, le pronostic, la prévention et le traitement du cancer du sein et de la néoplasie maligne du sein. L'invention concerne en outre des gènes qui sont exprimés différemment dans des tissus mammaires de patients atteints d'un cancer du sein contre ceux de tissus "sains" normaux. L'invention concerne également des gènes exprimés différemment pour l'identification de patients qui sont susceptibles de répondre à la chimiothérapie.

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