Steroid receptor modulator compounds and methods

Details Steroid receptor modulator compounds and methods Steroid receptor modulator compounds and methods

C - Chemistry, Metallurgy

07

D

C07D 215/06 (2006.01) A61K 31/435 (2006.01) A61K 31/505 (2006.01) C07D 215/16 (2006.01) C07D 221/18 (2006.01) C07D 221/20 (2006.01) C07D 311/80 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 471/04 (2006.01) C07D 491/04 (2006.01) C07D 491/044 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2208347

Non-steroidal compounds which are high affinity, high selectivity modulators for steroid receptors are disclosed. Also disclosed are pharmaceutical compositions incorporating such compounds, methods for employing the disclosed compounds and compositions for treating patients requiring steroid receptor agonist or antagonist therapy, intermediates useful in the preparation of the compounds and processes for the preparation of the steroid receptor modulator compounds.

On décrit des composés non stéroïdiens qui ont une grande affinité et une haute sélectivité vis-à-vis des récepteurs des stéroïdes. On décrit également des compositions pharmaceutiques comprenant de tels composés, des procédés pour les utiliser et des compositions pour traiter les patients nécessitant une thérapie faisant appel à des agonistes ou des antagonistes de ces récepteurs, ainsi que des intermédiaires et des procédés utiles pour la préparation des composés modulateurs des récepteurs des stéroïdes en question.

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