New applications of lysozyme dimer

Details New applications of lysozyme dimer New applications of lysozyme dimer

A - Human Necessities

61

K

A61K 38/47 (2006.01)

Patent

CA 2210091

The present invention relates to pharmaceutical compositions containing a lysozyme dimer, preferably of high purity, i.e. with about 10 wt.% or less of unintended by-products, and new applications thereof. Such applications include topical, oral and parenteral administration of said compositions for non-specific immunostimulation as a measure of prevention and/or therapeutic treatment of human and animal diseases comprising cancer, hair growth disorders, fish diseases and bee diseases. The non-specific stimulation of the immune system is induced by a single or repeated application of the lysozyme dimer composition, preferably at concentrations of 5 to 500 µg/kg body weight.

La présente invention se rapporte à des compositions pharmaceutiques contenant un dimère de lysozyme, de préférence très pur, c'est-à-dire possédant environ 10 % en poids ou moins de sous-produits non désirés, ainsi qu'à des nouvelles applications de celles-ci. De telles applications comprennent l'administration topique, orale et parentérale de ces compositions aux fins d'immunostimulation non spécifique, à titre de mesure préventive et/ou de traitement thérapeutique de maladies humaines et animales comprenant le cancer, des troubles de la croissance pileuse, des maladies du poisson et de l'abeille. La stimulation non spécifique du système immun est induite par une application unique ou répétée de la composition à base du dimère de lysozyme, de préférence à des concentrations de l'ordre de 5 à 100 µg par kilo de poids du corps.

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