C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/52 (2006.01) A61K 38/19 (2006.01) A61K 39/00 (2006.01) A61P 37/00 (2006.01) C07K 14/485 (2006.01) C07K 14/495 (2006.01) C07K 14/525 (2006.01) C07K 14/54 (2006.01) C07K 14/545 (2006.01) C07K 14/56 (2006.01) C07K 14/57 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2480996
The invention relates to a peptide which comprises between 5 and 40 amino acids, is obtained from a cytokine, and in which at least one of the amino acids contains at least one atom that is spaced (d) less than 5 angstroms from an atom of the receptor corresponding to said cytokine, the spacing (d) being evaluated on structural data, derivatives thereof, and an immunogenic compound comprising said peptide or peptide derivatives, the use of a peptide or peptide derivative or immunogenic compound for preparing a therapeutic or prophylactic medicament used for treating or preventing diseases that are associated with an excess or the presence of cytokines or for treating an autoimmune disease, and pharmaceutical compositions containing at least one inventive peptide or peptide derivative or immunogenic compound as an active principle.
Peptide de taille comprise entre 5 et 40 acides aminés, provenant d~une cytokine, dans lequel au moins un de ses acides aminés comporte au moins un de ses atomes espacé d~une distance d de moins de 5 angströms d~un atome du récepteur correspondant à ladite cytokine, l~espacement d étant évalué sur des données structurales, dérivés, composé immunogènes les comprenant, utilisation d~un peptide ou dérivé d~un peptide ou composé immunogène pour la préparation d~un médicament curatif ou préventif destiné au traitement ou à la prévention des affections liées à un excès ou à la présence de cytokines ou au traitement d~une maladie auto-immune et compositions pharmaceutiques qui renferment au moins un peptide ou dérivé d~un peptide ou composé immunogène ci-dessus à titre de principe actif.
Smart & Biggar
Vaxconsulting
LandOfFree
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