Splice variants of gdnf and uses thereof

Details Splice variants of gdnf and uses thereof Splice variants of gdnf and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 14/475 (2006.01) A61K 38/18 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) A61P 25/30 (2006.01) A61P 25/32 (2006.01)

Patent

CA 2703614

The present invention relates to Glial Cell Line-Derived Neurotrophic Factor (GDNF) protein and geneand is, in particular, directed to a novel splice variantof GDNF protein, which is encoded by a novel splice variant pre-(y) pro-GDNF, and secreted under biological regulation.

La présente invention concerne une protéine et un gène d'un facteur neurotrophique dérivé de cellules gliales (GDNF) et vise, en particulier, un nouveau variant d'épissage d'une protéine GDNF, laquelle est codée par un nouveau variant d'épissage pré-(y)pro-GDNF, et secrétée sous une régulation biologique.

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