C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/64 (2006.01) C12N 5/10 (2006.01) C12N 15/79 (2006.01)
Patent
CA 2587438
The present invention is of a method of producing proteins in mammalian cells using a permanent selection in the absence of cytotoxic drugs. Specifically, the present invention can be used to produce large quantities of highly pure human proteins which are suitable for pharmaceutical applications.
La présente invention a trait à un procédé de production de protéines dans des cellules mammaliennes mettant en oeuvre une sélection permanente en l'absence de médicaments cytotoxiques. De manière spécifique, l'invention peut être utilisée pour la production de grandes quantités de protéines humaines de haute pureté qui conviennent à des applications pharmaceutiques.
Assaraf Yehuda
Rothem Lilah
Borden Ladner Gervais Llp
Laboratoires Serono S.a.
Merck Serono Sa
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