Substituted pyrazole carboxylic acids used to combat anaemias

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 231/12 (2006.01) A61K 31/415 (2006.01) A61P 7/06 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2361816

The invention relates to methods for the production of substituted pyrazole carboxylic acids of general formula (I). The key step is cyclization with hydrazines followed by saponification. The substituted pyrazole carboxylic acids are used as medicaments, especially as medicaments in the treatment and prophylaxis of anaemias.

L'invention concerne des procédés de production d'acides pyrazolcarboxyliques substitués de formule générale (I). L'étape-clé de ces procédés est la cyclisation avec des hydrazines suivie par une saponification. Ces acides pyrazolcarboxyliques substitués sont utilisés comme médicament, notamment pour le traitement et la prophylaxie d'anémies.

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