C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/16 (2006.01) A61K 31/4025 (2006.01) A61K 31/415 (2006.01) A61K 31/426 (2006.01) A61K 31/4439 (2006.01) A61K 31/445 (2006.01) A61K 31/5375 (2006.01) A61P 25/28 (2006.01) C07D 211/60 (2006.01) C07D 231/04 (2006.01) C07D 265/30 (2006.01) C07D 277/06 (2006.01) C07D 401/06 (2006.01) C07D 409/12 (2006.01)
Patent
CA 2602802
This invention relates to neurotrophic low molecular weight, small molecule heterocyclic thioesters and ketones having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
Hamilton Gregory S.
Li Jia-He
Gliamed Inc.
Ridout & Maybee Llp
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