3-fluoro-piperidine t-type calcium channel antagonists

Details 3-fluoro-piperidine t-type calcium channel antagonists 3-fluoro-piperidine t-type calcium channel antagonists

C - Chemistry, Metallurgy

07

D

C07D 211/38 (2006.01) A61K 31/445 (2006.01) C07D 211/06 (2006.01)

Patent

CA 2611153

The present invention is directed to 3-fluoro-piperidine compounds which are antagonists of T-type calcium channels, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which T-type calcium channels are involved.

Ces composés 3-fluoro-pipéridine sont des antagonistes des canaux calciques de type T et servent au traitement ou à la prévention de troubles neurologiques ou psychiatriques en rapport avec des canaux calciques de type T. des compositions pharmaceutiques comprennent ces composés et on les utilise pour prévenir ou traiter de telles maladies.

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