Compositions and methods including expression and...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/59 (2006.01) A61K 38/16 (2006.01) A61K 38/24 (2006.01) A61P 15/00 (2006.01) C12N 15/16 (2006.01)

Patent

CA 2685437

The present invention provides methods of producing biologically active recombinant bFSH and methods of increasing reproduction in mammals, particularly bovine, using recombinant bFSH. Also provided are methods of producing single chain recombinant bFSH. The recombinant bFSH of the present invention increases superovulation, embryo development, and reproductive efficiency in cattle and other ungulates.

L'invention porte sur des méthodes de production de bFSH biologiquement actif de recombinaison, et sur des méthodes accroissant la reproduction chez les mammifères, particulièrement les bovins, utilisant le bFSH de recombinaison. L'invention porte en outre sur des méthodes de production de bFSH de recombinaison à chaîne unique. Le bFSH de recombinaison de l'invention accroît la surovulation, le développement d'embryons et l'efficacité reproductrice du bétail et d'autres ongulés.

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