Il-17a and il-17f antagonists and methods of using the same

Details Il-17a and il-17f antagonists and methods of using the same Il-17a and il-17f antagonists and methods of using the same

C - Chemistry, Metallurgy

07

K

C07K 14/715 (2006.01) A61K 38/17 (2006.01) A61K 38/20 (2006.01) A61K 39/395 (2006.01) A61P 29/00 (2006.01) C07K 16/28 (2006.01) C12P 21/08 (2006.01) C07K 14/52 (2006.01)

Patent

CA 2621623

The present invention relates antagonists of IL-17A and IL-17F. The antagonists of the invention are based on IL-17RC alone or on both IL-17RC and IL-17RA ("IL-17RC/IL-17RA") . Such antagonists serve to block, inhibit, reduce, antagonize or neutralize the activity of IL-17F, IL-17A, or both IL- 17A and IL-17F. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. IL- 17RA is a receptor for IL-17A and IL-17RC is a common receptor for both IL-17A and IL-17F. The present invention includes soluble IL-17A and IL-17F antagonists, as well as methods for using the same.

L'invention concerne des antagonistes anti IL-17A et IL-17F. Ces antagonistes sont basés soit sur IL-17RC seul, soit à la fois sur IL-17RC et IL-17RA ("IL-17RC/TL-17RA"). Ces antagonistes servent à bloquer, inhiber, réduire, contrer ou neutraliser l'activité de IL-17F, IL-17A ou les deux IL-17A et IL-17F. IL-17A et IL-17F sont des cytokines jouant un rôle dans des états inflammatoires et des maladies humaines. IL- 17RA est un récepteur de IL-17A et IL-17RC est un récepteur commun à IL-17A et IL-17F. L'invention concerne des antagonistes solubles anti IL-17A et anti IL-17F, ainsi que leurs méthodes d'utilisation.

Affiliated with

Also associated with

Rating

Il-17a and il-17f antagonists and methods of using the same does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Il-17a and il-17f antagonists and methods of using the same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Il-17a and il-17f antagonists and methods of using the same will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1971372