C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 17/08 (2006.01) A61K 31/70 (2006.01) A61P 31/04 (2006.01) A61P 33/02 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2349338
This invention relates to compounds of formula (I) wherein a, R1, R2, R3, R4, R5, R6 and X are each as defined above, and to pharmaceutically acceptable salts thereof, useful as potent antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula (I) and to methods of treating bacterial and protozoal infections by administering the compounds of formula (I).
Composés de formule (I) dans laquelle a, R<1>, R<2>, R<3>, R<4>, R<5>, R<6> et X sont tels que définis dans le descriptif, ainsi que sels desdits composés acceptables sur le plan pharmaceutique, qui sont utiles en tant qu'agents antibactériens et antiprotozoaires puissants pouvant être utilisés pour traiter diverses infections bactériennes et protozooses, ainsi que des états pathologiques liés à ces infections. La présente invention concerne également des compositions pharmaceutiques contenant les composés de formule (I) et les procédés de traitement d'infections bactériennes et de protozooses par l'administration desdits composés de formule (I).
Pfizer Products Inc.
Smart & Biggar
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