Therapeutic uses of known ester and amide compounds

Details Therapeutic uses of known ester and amide compounds Therapeutic uses of known ester and amide compounds

A - Human Necessities

61

K

A61K 31/47 (2006.01) A61K 31/16 (2006.01) A61K 31/245 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2130291

ABSTRACT OF THE DISCLOSURE A number of new therapeutic uses have been found for compounds such as known local anesthetics which are quite different from the present therapeutic uses of these drugs. The uses include, for example; modulating lymphocytes, macrophages and other immune cell functions, or PMN functions; inhibiting the cytotoxic effect of polymorphonuclear neutrophils leucocytes; providing a protective effect on plasma cell membranes; and providing an antidote against intoxication by intoxicants. A further new use has been found for treating subject suffering from neoplastic diseases of diverse cell or tissue origin by the administration of an effective amount of lidocaine or a related substance. It has been found that this new use provides a reduction and/or inhibition of tumor growth.

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