Formulations of active components in the form of a solid...

Details Formulations of active components in the form of a solid... Formulations of active components in the form of a solid...

A - Human Necessities

61

K

A61K 47/34 (2006.01) A61K 9/10 (2006.01) A61K 9/16 (2006.01) A61K 31/4422 (2006.01) A61K 47/32 (2006.01)

Patent

CA 2396722

Formulations of active compounds in the form of a solid dispersion, where the solid dispersion is formed from at least one active component and a carrier characterized in that the carrier is a mixture of polyvinylpyrrolidone (PVP) with a weight average molecular weight of <= 1 500 000 Da and of a polyethylene glycol (PEG) which is semi-solid or solid at temperatures of 17 to 22 °C and has an average molar mass of 950 to 3300 Da.

L'invention concerne des formulations de principes actifs se présentant sous la forme d'une dispersion solide constituée d'au moins un principe actif et un excipient. L'invention est caractérisée en ce que l'excipient est un mélange de polyvinylpyrrolidone (PVP) présentant un poids moléculaire moyen en poids </= 1 500 000 daltons et un polyéthylèneglycol (PEG) semi-solide ou solide à des température comprises entre 17 et 22 DEG C, présentant un poids moléculaire moyen compris entre 950 et 3 300 daltons.

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