C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/85 (2006.01) A01K 67/027 (2006.01) C07K 14/47 (2006.01) C12N 5/10 (2006.01) C12N 15/90 (2006.01)
Patent
CA 2206789
The present invention relates to a transgenic nonhuman animal lacking native amyloid precursor protein. The transgenic mouse of the invention may be used in the study of Alzheimer's Disease and disorders involving the central nervous system.
L'invention concerne un animal transgénique non humain, présentant une carence en protéine précurseur d'amyloïde native. La souris transgénique selon l'invention peut être utilisée dans l'étude de la maladie d'Alzheimer et de troubles impliquant le système nerveux central.
Chen Howard Y.
Trumbauer Myrna E.
Van Der Ploeg Leonardus H.t.
Zheng Hui
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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